人 pTau212 抗体对
01AB00088
pTau212 is a phosphorylated tau biomarker that reflects tau pathology in Alzheimer’s disease, and it is being studied as a blood-based marker for earlier detection and disease staging. Like tau in general, it is linked to the protein’s normal role in stabilizing microtubules and supporting neuronal structure, but when tau becomes abnormally phosphorylated it can lose that function and contribute to toxic aggregation and neurofibrillary tangle formation. Research descriptions of pTau212 emphasize that it may improve discrimination of Alzheimer’s pathology and complement established markers such as pTau181 and pTau217. Its main disease relevance is therefore as a biomarker for Alzheimer’s-related amyloid and tau pathology.
| 规格 | 起售价 |
|---|---|
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技术参数
- 靶点基因名
- MAPT
- 基因别名
- MAPTL; MTBT1; TAU
- 蛋白别名
- Microtubule-associated protein tau; pTau212
- UniProt
- P10636-8
- 物种
- Human
产品详情
- 靶点名称
- pTau212
- 蛋白名称
- Microtubule-associated protein tau
- 靶点基因名
- MAPT
- 基因别名
- MAPTL; MTBT1; TAU
- UniProt
- P10636-8
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
pTau212 is a phosphorylated tau biomarker that reflects tau pathology in Alzheimer’s disease, and it is being studied as a blood-based marker for earlier detection and disease staging. Like tau in general, it is linked to the protein’s normal role in stabilizing microtubules and supporting neuronal structure, but when tau becomes abnormally phosphorylated it can lose that function and contribute to toxic aggregation and neurofibrillary tangle formation. Research descriptions of pTau212 emphasize that it may improve discrimination of Alzheimer’s pathology and complement established markers such as pTau181 and pTau217. Its main disease relevance is therefore as a biomarker for Alzheimer’s-related amyloid and tau pathology.