人 PRR5 抗体对
01AB00355
Proline rich 5 (PRR5), also known as LAYN, is a protein encoded by the PRR5 gene in humans. It is characterized by its proline-rich domains, which facilitate protein-protein interactions, particularly with signaling complexes like mTORC2 (mechanistic target of rapamycin complex 2). PRR5 is involved in regulating cellular processes such as cell growth, metabolism, and cytoskeletal organization. Structurally, it has a molecular weight of approximately 40 kDa and contains conserved regions that bind to components of the mTOR pathway, influencing Akt signaling and downstream pathways linked to cell survival and proliferation. PRR5 is implicated in cancer progression, with studies associating its overexpression with prostate cancer aggressiveness and colorectal cancer metastasis, likely due to its role in enhancing tumor cell survival and immune evasion.
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技术参数
- 靶点基因名
- PRR5
- 基因别名
- PROTOR1
- 蛋白别名
- proline rich 5; PRR5
- UniProt
- P85299
- 物种
- Human
产品详情
- 靶点名称
- PRR5
- 蛋白名称
- proline rich 5
- 蛋白别名
- Proline-rich protein 5; Protein observed with Rictor-1; Protor-1
- 靶点基因名
- PRR5
- 基因别名
- PROTOR1
- UniProt
- P85299
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Proline rich 5 (PRR5), also known as LAYN, is a protein encoded by the PRR5 gene in humans. It is characterized by its proline-rich domains, which facilitate protein-protein interactions, particularly with signaling complexes like mTORC2 (mechanistic target of rapamycin complex 2). PRR5 is involved in regulating cellular processes such as cell growth, metabolism, and cytoskeletal organization. Structurally, it has a molecular weight of approximately 40 kDa and contains conserved regions that bind to components of the mTOR pathway, influencing Akt signaling and downstream pathways linked to cell survival and proliferation. PRR5 is implicated in cancer progression, with studies associating its overexpression with prostate cancer aggressiveness and colorectal cancer metastasis, likely due to its role in enhancing tumor cell survival and immune evasion.