人 Proteasome beta 9 抗体对
01AB02873
Proteasome 20S subunit beta 9 (Proteasome beta 9) is a component of the 20S core particle, the central catalytic unit of the proteasome complex responsible for protein degradation. It assembles into the inner beta-rings of the four-stacked ring structure. Synthesized with an N-terminal propeptide that is removed during assembly, this subunit plays a critical structural and regulatory role in core particle formation and stability, supporting the proper positioning of catalytic subunits. Defects in proteasome assembly or function compromise proteostasis, contributing to diverse pathologies including neurodegenerative diseases, inflammatory disorders, and cancer.
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技术参数
- 靶点基因名
- PSMB9
- 基因别名
- LMP2; PSMB6i; RING12
- 蛋白别名
- proteasome 20S subunit beta 9; Proteasome beta 9
- UniProt
- P28065
- 物种
- Human
产品详情
- 靶点名称
- Proteasome beta 9
- 蛋白名称
- proteasome 20S subunit beta 9
- 蛋白别名
- Proteasome subunit beta type-9; Low molecular mass protein 2; Macropain chain 7; Multicatalytic endopeptidase complex chain 7; Proteasome chain 7; Proteasome subunit beta-1i; Really interesting new gene 12 protein
- 靶点基因名
- PSMB9
- 基因别名
- LMP2; PSMB6i; RING12
- UniProt
- P28065
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Proteasome 20S subunit beta 9 (Proteasome beta 9) is a component of the 20S core particle, the central catalytic unit of the proteasome complex responsible for protein degradation. It assembles into the inner beta-rings of the four-stacked ring structure. Synthesized with an N-terminal propeptide that is removed during assembly, this subunit plays a critical structural and regulatory role in core particle formation and stability, supporting the proper positioning of catalytic subunits. Defects in proteasome assembly or function compromise proteostasis, contributing to diverse pathologies including neurodegenerative diseases, inflammatory disorders, and cancer.