人 Prolactin 抗体对
01AB03556
Prolactin (PRL) is a hormone produced by the pituitary gland that plays a crucial role in various physiological processes. It is primarily known for its involvement in lactation and breast development during pregnancy, but it also has diverse effects on the immune system, metabolism, and the central nervous system. PRL exhibits immunomodulatory properties, influencing the function and proliferation of lymphocytes, macrophages, and other immune cells. Elevated PRL levels have been associated with autoimmune diseases like systemic lupus erythematosus, rheumatoid arthritis, and peripartum cardiomyopathy. Additionally, PRL has been implicated in neuropsychiatric disorders such as depression and schizophrenia, as well as neurogenesis and blood-brain barrier regulation. Furthermore, hyperprolactinemia (high PRL levels) can lead to sexual dysfunction, infertility, and an increased risk of certain cancers.
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技术参数
- 靶点基因名
- PRL
- 蛋白别名
- prolactin; Prolactin
- UniProt
- P01236
- 物种
- Human
产品详情
- 靶点名称
- Prolactin
- 蛋白名称
- prolactin
- 蛋白别名
- Prolactin; PRL
- 靶点基因名
- PRL
- UniProt
- P01236
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Prolactin (PRL) is a hormone produced by the pituitary gland that plays a crucial role in various physiological processes. It is primarily known for its involvement in lactation and breast development during pregnancy, but it also has diverse effects on the immune system, metabolism, and the central nervous system. PRL exhibits immunomodulatory properties, influencing the function and proliferation of lymphocytes, macrophages, and other immune cells. Elevated PRL levels have been associated with autoimmune diseases like systemic lupus erythematosus, rheumatoid arthritis, and peripartum cardiomyopathy. Additionally, PRL has been implicated in neuropsychiatric disorders such as depression and schizophrenia, as well as neurogenesis and blood-brain barrier regulation. Furthermore, hyperprolactinemia (high PRL levels) can lead to sexual dysfunction, infertility, and an increased risk of certain cancers.