人 PPP1R9B 抗体对
01AB03495
Neurabin-2 (PPP1R9B) is a protein that belongs to the neurabin family and is characterized by its role in linking the actin cytoskeleton to various signaling pathways. It contains an F-actin-binding domain and a PDZ domain, allowing it to interact with multiple proteins and facilitate cellular processes such as synaptic signaling and cell adhesion. Neurabin-2 is predominantly expressed in the brain, where it plays a critical role in the organization of the postsynaptic density, thereby influencing synaptic plasticity and neuronal communication. Dysregulation of neurabin-2 has been implicated in several neurological disorders, including schizophrenia and autism spectrum disorders, where altered synaptic function may contribute to disease pathology. Additionally, its involvement in cancer progression has been noted, as changes in neurabin-2 expression can affect tumor cell migration and invasion.
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技术参数
- 靶点基因名
- PPP1R9B
- 基因别名
- PPP1R6
- 蛋白别名
- protein phosphatase 1 regulatory subunit 9B; PPP1R9B
- UniProt
- Q96SB3
- 物种
- Human
产品详情
- 靶点名称
- PPP1R9B
- 蛋白名称
- protein phosphatase 1 regulatory subunit 9B
- 蛋白别名
- Neurabin-2; Neurabin-II; Protein phosphatase 1 regulatory subunit 9B; Spinophilin
- 靶点基因名
- PPP1R9B
- 基因别名
- PPP1R6
- UniProt
- Q96SB3
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Neurabin-2 (PPP1R9B) is a protein that belongs to the neurabin family and is characterized by its role in linking the actin cytoskeleton to various signaling pathways. It contains an F-actin-binding domain and a PDZ domain, allowing it to interact with multiple proteins and facilitate cellular processes such as synaptic signaling and cell adhesion. Neurabin-2 is predominantly expressed in the brain, where it plays a critical role in the organization of the postsynaptic density, thereby influencing synaptic plasticity and neuronal communication. Dysregulation of neurabin-2 has been implicated in several neurological disorders, including schizophrenia and autism spectrum disorders, where altered synaptic function may contribute to disease pathology. Additionally, its involvement in cancer progression has been noted, as changes in neurabin-2 expression can affect tumor cell migration and invasion.