人塑蛋白 L 抗体对
01AB00295
Lymphocyte cytosolic protein 1 (LCP1), also known as plastin-2, is an actin-binding protein that plays a crucial role in cell processes and immune cell activity. It is specifically expressed in hemopoietic cell lineages and has been found in many types of malignant human cells of non-hemopoietic origin, suggesting its expression is induced during tumorigenesis in solid tissues. LCP1 has been identified as a potential biomarker for various cancers, including triple-negative breast cancer (TNBC), where high expression of LCP1 is associated with favorable survival outcomes and immune cell infiltration, particularly M1 and M2 macrophages. Its functions extend to the immune system, affecting the behavior of various immune cells such as macrophages, neutrophils, B-cells, and T-cells.
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技术参数
- 靶点基因名
- LCP1
- 基因别名
- PLS2
- 蛋白别名
- lymphocyte cytosolic protein 1; Plastin L
- UniProt
- P13796
- 物种
- Human
产品详情
- 靶点名称
- Plastin L
- 蛋白名称
- lymphocyte cytosolic protein 1
- 蛋白别名
- Plastin-2; L-plastin; LC64P; Lymphocyte cytosolic protein 1; LCP-1
- 靶点基因名
- LCP1
- 基因别名
- PLS2
- UniProt
- P13796
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Lymphocyte cytosolic protein 1 (LCP1), also known as plastin-2, is an actin-binding protein that plays a crucial role in cell processes and immune cell activity. It is specifically expressed in hemopoietic cell lineages and has been found in many types of malignant human cells of non-hemopoietic origin, suggesting its expression is induced during tumorigenesis in solid tissues. LCP1 has been identified as a potential biomarker for various cancers, including triple-negative breast cancer (TNBC), where high expression of LCP1 is associated with favorable survival outcomes and immune cell infiltration, particularly M1 and M2 macrophages. Its functions extend to the immune system, affecting the behavior of various immune cells such as macrophages, neutrophils, B-cells, and T-cells.