人 Peroxiredoxin-6 抗体对
01AB00562
Peroxiredoxin 6 (PRDX6) is a multifunctional enzyme that plays a crucial role in protecting cells from oxidative stress. It is a member of the peroxiredoxin family of antioxidant enzymes and is widely distributed in various organs, particularly in the lungs. PRDX6 has two distinct active sites, enabling it to reduce hydrogen peroxide (H2O2) and short-chain organic, fatty acid, and phospholipid hydroperoxides, thereby protecting cells from oxidative injury. It also exhibits phospholipase A2 (PLA2) activity, which is essential for the repair of peroxidized cell membranes and the regulation of phospholipid turnover. PRDX6 has been implicated in various diseases, including neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease, where its PLA2 activity can either protect against or exacerbate oxidative stress depending on the context. Overall, PRDX6 is a critical enzyme for maintaining cellular redox balance and preventing oxidative damage.
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技术参数
- 靶点基因名
- PRDX6
- 基因别名
- AOP2; KIAA0106
- 蛋白别名
- peroxiredoxin 6; Peroxiredoxin-6
- UniProt
- P30041
- 物种
- Human
产品详情
- 靶点名称
- Peroxiredoxin-6
- 蛋白名称
- peroxiredoxin 6
- 蛋白别名
- Peroxiredoxin-6; 1-Cys peroxiredoxin; 1-Cys PRX; 24 kDa protein; Acidic calcium-independent phospholipase A2; aiPLA2; Antioxidant protein 2; Glutathione-dependent peroxiredoxin; Liver 2D page spot 40; Lysophosphatidylcholine acyltransferase 5; LPC acyltransferase 5; LPCAT-5; Lyso-PC acyltransferase 5; Non-selenium glutathione peroxidase; NSGPx; Red blood cells page spot 12
- 靶点基因名
- PRDX6
- 基因别名
- AOP2; KIAA0106
- UniProt
- P30041
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Peroxiredoxin 6 (PRDX6) is a multifunctional enzyme that plays a crucial role in protecting cells from oxidative stress. It is a member of the peroxiredoxin family of antioxidant enzymes and is widely distributed in various organs, particularly in the lungs. PRDX6 has two distinct active sites, enabling it to reduce hydrogen peroxide (H2O2) and short-chain organic, fatty acid, and phospholipid hydroperoxides, thereby protecting cells from oxidative injury. It also exhibits phospholipase A2 (PLA2) activity, which is essential for the repair of peroxidized cell membranes and the regulation of phospholipid turnover. PRDX6 has been implicated in various diseases, including neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease, where its PLA2 activity can either protect against or exacerbate oxidative stress depending on the context. Overall, PRDX6 is a critical enzyme for maintaining cellular redox balance and preventing oxidative damage.