人 NTF3 抗体对
01AB00328
Neurotrophin 3 (NTF3) is a member of the neurotrophin family, which plays a crucial role in the survival, differentiation, and maintenance of specific neuronal populations in both the central and peripheral nervous systems. The protein is derived from a precursor of 257 amino acids, with the active form consisting of 119 amino acids after processing. NTF3 primarily interacts with the TrkC receptor, promoting the growth and survival of sensory neurons, particularly those involved in proprioception and visceral sensations. Dysregulation of NTF3 has been implicated in various neurological disorders, including neuropathic pain, where altered levels may affect neuronal survival and function. Additionally, it has been studied in the context of neurodegenerative diseases like Alzheimer's and Parkinson's, suggesting that it may have protective effects against neuronal loss.
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技术参数
- 靶点基因名
- NTF3
- 蛋白别名
- neurotrophin 3; NTF3
- UniProt
- P20783
- 物种
- Human
产品详情
- 靶点名称
- NTF3
- 蛋白名称
- neurotrophin 3
- 蛋白别名
- Neurotrophin-3; NT-3; HDNF; Nerve growth factor 2; NGF-2; Neurotrophic factor
- 靶点基因名
- NTF3
- UniProt
- P20783
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Neurotrophin 3 (NTF3) is a member of the neurotrophin family, which plays a crucial role in the survival, differentiation, and maintenance of specific neuronal populations in both the central and peripheral nervous systems. The protein is derived from a precursor of 257 amino acids, with the active form consisting of 119 amino acids after processing. NTF3 primarily interacts with the TrkC receptor, promoting the growth and survival of sensory neurons, particularly those involved in proprioception and visceral sensations. Dysregulation of NTF3 has been implicated in various neurological disorders, including neuropathic pain, where altered levels may affect neuronal survival and function. Additionally, it has been studied in the context of neurodegenerative diseases like Alzheimer's and Parkinson's, suggesting that it may have protective effects against neuronal loss.