人 NPPC 抗体对
01AB00323
Natriuretic peptide C (NPPC), also known as C-type natriuretic peptide (CNP), is a protein encoded by the NPPC gene in humans. It is part of the natriuretic peptide family, which includes atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP). Unlike ANP and BNP, CNP does not have direct natriuretic activity but instead acts as a selective agonist for the B-type natriuretic receptor (NPRB). CNP is synthesized and secreted from the endothelium in response to stimuli such as shear stress and proinflammatory cytokines. It plays a crucial role in endochondral ossification by regulating cartilaginous growth plate chondrocytes' proliferation and differentiation. CNP is also implicated in various physiological processes, including body fluid homeostasis and blood pressure control, and has been studied for its roles in reproduction, pregnancy, and fetal development.
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技术参数
- 靶点基因名
- NPPC
- 基因别名
- CNP2
- 蛋白别名
- natriuretic peptide C; NPPC
- UniProt
- P23582
- 物种
- Human
产品详情
- 靶点名称
- NPPC
- 蛋白名称
- natriuretic peptide C
- 蛋白别名
- C-type natriuretic peptide [Cleaved into: CNP-22; CNP-29; CNP-53]
- 靶点基因名
- NPPC
- 基因别名
- CNP2
- UniProt
- P23582
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Natriuretic peptide C (NPPC), also known as C-type natriuretic peptide (CNP), is a protein encoded by the NPPC gene in humans. It is part of the natriuretic peptide family, which includes atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP). Unlike ANP and BNP, CNP does not have direct natriuretic activity but instead acts as a selective agonist for the B-type natriuretic receptor (NPRB). CNP is synthesized and secreted from the endothelium in response to stimuli such as shear stress and proinflammatory cytokines. It plays a crucial role in endochondral ossification by regulating cartilaginous growth plate chondrocytes' proliferation and differentiation. CNP is also implicated in various physiological processes, including body fluid homeostasis and blood pressure control, and has been studied for its roles in reproduction, pregnancy, and fetal development.