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人 NPPC 抗体对
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人 NPPC 抗体对

01AB00322

Natriuretic peptide C (NPPC), also known as C-type natriuretic peptide (CNP), is a protein encoded by the NPPC gene in humans. It is part of the natriuretic peptide family, which includes atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP). Unlike ANP and BNP, CNP does not have direct natriuretic activity but instead acts as a selective agonist for the B-type natriuretic receptor (NPRB). CNP is synthesized and secreted from the endothelium in response to stimuli such as shear stress and proinflammatory cytokines. It plays a crucial role in endochondral ossification by regulating cartilaginous growth plate chondrocytes' proliferation and differentiation. CNP is also implicated in various physiological processes, including body fluid homeostasis and blood pressure control, and has been studied for its roles in reproduction, pregnancy, and fetal development.

Human
规格起售价
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技术参数

靶点基因名
NPPC
基因别名
CNP2
蛋白别名
natriuretic peptide C; NPPC
UniProt
P23582
物种
Human

产品详情

靶点名称
NPPC
蛋白名称
natriuretic peptide C
蛋白别名
C-type natriuretic peptide [Cleaved into: CNP-22; CNP-29; CNP-53]
靶点基因名
NPPC
基因别名
CNP2
UniProt
P23582
来源物种
Homo sapiens (Human)
物种反应性
Human

背景介绍

Natriuretic peptide C (NPPC), also known as C-type natriuretic peptide (CNP), is a protein encoded by the NPPC gene in humans. It is part of the natriuretic peptide family, which includes atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP). Unlike ANP and BNP, CNP does not have direct natriuretic activity but instead acts as a selective agonist for the B-type natriuretic receptor (NPRB). CNP is synthesized and secreted from the endothelium in response to stimuli such as shear stress and proinflammatory cytokines. It plays a crucial role in endochondral ossification by regulating cartilaginous growth plate chondrocytes' proliferation and differentiation. CNP is also implicated in various physiological processes, including body fluid homeostasis and blood pressure control, and has been studied for its roles in reproduction, pregnancy, and fetal development.