抗人 MMP10 抗体对
01AB03336
Stromelysin-2, also known as Matrix Metalloproteinase-10 (MMP-10), is a secreted enzyme that belongs to the matrix metalloproteinase family, which is involved in the degradation of the extracellular matrix. MMP-10 plays essential roles in various physiological processes, including tissue remodeling, wound healing, and skeletal development. It is particularly noted for its ability to degrade components such as proteoglycans and fibronectin. Dysregulation of MMP-10 has been implicated in several pathological conditions, including cancer, where its overexpression is associated with tumor progression and metastasis. For example, elevated levels of MMP-10 have been linked to increased cancer stem cell vitality and poor prognosis in oral cancer patients. Additionally, MMP-10's involvement in inflammatory processes suggests a role in diseases such as arthritis and cardiovascular disorders.
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技术参数
- 靶点基因名
- MMP10
- 基因别名
- STMY2
- 蛋白别名
- matrix metallopeptidase 10; MMP10
- UniProt
- P09238
- 物种
- Human
产品详情
- 靶点名称
- MMP10
- 蛋白名称
- matrix metallopeptidase 10
- 蛋白别名
- Stromelysin-2; SL-2; Matrix metalloproteinase-10; MMP-10; Transin-2
- 靶点基因名
- MMP10
- 基因别名
- STMY2
- UniProt
- P09238
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Stromelysin-2, also known as Matrix Metalloproteinase-10 (MMP-10), is a secreted enzyme that belongs to the matrix metalloproteinase family, which is involved in the degradation of the extracellular matrix. MMP-10 plays essential roles in various physiological processes, including tissue remodeling, wound healing, and skeletal development. It is particularly noted for its ability to degrade components such as proteoglycans and fibronectin. Dysregulation of MMP-10 has been implicated in several pathological conditions, including cancer, where its overexpression is associated with tumor progression and metastasis. For example, elevated levels of MMP-10 have been linked to increased cancer stem cell vitality and poor prognosis in oral cancer patients. Additionally, MMP-10's involvement in inflammatory processes suggests a role in diseases such as arthritis and cardiovascular disorders.