抗人 MILR1 抗体对
01AB03331
Allergin-1 (MILR1) is a protein that belongs to the immunoglobulin superfamily and is primarily expressed in various tissues, including the lungs and skin. It functions as a cell surface receptor that plays a significant role in immune responses, particularly in the context of allergic reactions and asthma. MILR1 is known to interact with specific ligands, facilitating cellular signaling pathways that lead to the activation of immune cells. Its expression is often upregulated in allergic conditions, contributing to the pathophysiology of asthma and other hypersensitivity disorders. Dysregulation of MILR1 has been linked to increased susceptibility to allergic diseases, as it may enhance the activation and proliferation of mast cells and eosinophils, which are critical players in allergic inflammation.
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技术参数
- 靶点基因名
- MILR1
- 基因别名
- C17orf60; MCA32
- 蛋白别名
- mast cell immunoglobulin like receptor 1; MILR1
- UniProt
- Q7Z6M3
- 物种
- Human
产品详情
- 靶点名称
- MILR1
- 蛋白名称
- mast cell immunoglobulin like receptor 1
- 蛋白别名
- Allergin-1; Allergy inhibitory receptor 1; Mast cell antigen 32; MCA-32; Mast cell immunoglobulin-like receptor 1
- 靶点基因名
- MILR1
- 基因别名
- C17orf60; MCA32
- UniProt
- Q7Z6M3
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Allergin-1 (MILR1) is a protein that belongs to the immunoglobulin superfamily and is primarily expressed in various tissues, including the lungs and skin. It functions as a cell surface receptor that plays a significant role in immune responses, particularly in the context of allergic reactions and asthma. MILR1 is known to interact with specific ligands, facilitating cellular signaling pathways that lead to the activation of immune cells. Its expression is often upregulated in allergic conditions, contributing to the pathophysiology of asthma and other hypersensitivity disorders. Dysregulation of MILR1 has been linked to increased susceptibility to allergic diseases, as it may enhance the activation and proliferation of mast cells and eosinophils, which are critical players in allergic inflammation.