人 METRNL 抗体对
01AB03277
Meteorin like, glial cell differentiation regulator (METRNL) is a secreted pleiotropic factor expressed in adipose tissue, muscle, and the nervous system. It functions as a neurotrophic factor supporting neuronal survival and neurite outgrowth, and as an adipokine that enhances beige fat thermogenesis and insulin sensitivity. METRNL modulates immune responses by promoting alternative macrophage activation. Its levels are dynamically regulated in metabolic conditions such as obesity and diabetes. Due to its beneficial effects on metabolism and inflammation, METRNL is investigated as a biomarker and therapeutic target for metabolic syndrome and cardiovascular diseases.
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技术参数
- 靶点基因名
- METRNL
- 蛋白别名
- meteorin like, glial cell differentiation regulator; METRNL
- UniProt
- Q641Q3
- 物种
- Human
产品详情
- 靶点名称
- METRNL
- 蛋白名称
- meteorin like, glial cell differentiation regulator
- 蛋白别名
- Meteorin-like protein; Subfatin
- 靶点基因名
- METRNL
- UniProt
- Q641Q3
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Meteorin like, glial cell differentiation regulator (METRNL) is a secreted pleiotropic factor expressed in adipose tissue, muscle, and the nervous system. It functions as a neurotrophic factor supporting neuronal survival and neurite outgrowth, and as an adipokine that enhances beige fat thermogenesis and insulin sensitivity. METRNL modulates immune responses by promoting alternative macrophage activation. Its levels are dynamically regulated in metabolic conditions such as obesity and diabetes. Due to its beneficial effects on metabolism and inflammation, METRNL is investigated as a biomarker and therapeutic target for metabolic syndrome and cardiovascular diseases.