人 MESD 抗体对
01AB00305
Mesoderm development LRP chaperone (MESD) is a protein crucial for the proper functioning of the Wnt signaling pathway, particularly through its role in chaperoning the coreceptors LRP5 and LRP6 to the plasma membrane. It is involved in various biological processes, including ossification and protein folding, and is predicted to enable low-density lipoprotein particle receptor binding activity. In humans, MESD is encoded by the gene located on chromosome 15. Notably, loss-of-function mutations in the MESD gene have been associated with Osteogenesis imperfecta type 2, a severe form of brittle bone disease characterized by bone fragility and other skeletal abnormalities.
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技术参数
- 靶点基因名
- MESD
- 基因别名
- KIAA0081; MESDC2; MESDM
- 蛋白别名
- mesoderm development LRP chaperone; MESD
- UniProt
- Q14696
- 物种
- Human
产品详情
- 靶点名称
- MESD
- 蛋白名称
- mesoderm development LRP chaperone
- 蛋白别名
- LRP chaperone MESD; LDLR chaperone MESD; Mesoderm development LRP chaperone MESD; Mesoderm development candidate 2; Mesoderm development protein; Renal carcinoma antigen NY-REN-61
- 靶点基因名
- MESD
- 基因别名
- KIAA0081; MESDC2; MESDM
- UniProt
- Q14696
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Mesoderm development LRP chaperone (MESD) is a protein crucial for the proper functioning of the Wnt signaling pathway, particularly through its role in chaperoning the coreceptors LRP5 and LRP6 to the plasma membrane. It is involved in various biological processes, including ossification and protein folding, and is predicted to enable low-density lipoprotein particle receptor binding activity. In humans, MESD is encoded by the gene located on chromosome 15. Notably, loss-of-function mutations in the MESD gene have been associated with Osteogenesis imperfecta type 2, a severe form of brittle bone disease characterized by bone fragility and other skeletal abnormalities.