抗人 LZIC 抗体对
01AB01986
Leucine zipper and CTNNBIP1 domain containing (LZIC) is a cytoplasmic and nuclear protein characterized by an N-terminal leucine-zipper-like region and a C-terminal ICAT-like domain. These structural motifs suggest a primary role in protein-protein interactions and the modulation of the Wnt/β-catenin signaling pathway. LZIC is broadly expressed across various tissues and has been implicated in the cellular response to DNA damage, particularly following ionizing radiation. Functional studies indicate that LZIC levels influence radiation sensitivity and cell-cycle regulation, positioning the protein as a potential modulator of survival pathways and a candidate biomarker for cellular stress responses.
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技术参数
- 靶点基因名
- LZIC
- 蛋白别名
- leucine zipper and CTNNBIP1 domain containing; LZIC
- UniProt
- Q8WZA0
- 物种
- Human
产品详情
- 靶点名称
- LZIC
- 蛋白名称
- leucine zipper and CTNNBIP1 domain containing
- 蛋白别名
- Protein LZIC; Leucine zipper and CTNNBIP1 domain-containing protein; Leucine zipper and ICAT homologous domain-containing protein
- 靶点基因名
- LZIC
- UniProt
- Q8WZA0
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Leucine zipper and CTNNBIP1 domain containing (LZIC) is a cytoplasmic and nuclear protein characterized by an N-terminal leucine-zipper-like region and a C-terminal ICAT-like domain. These structural motifs suggest a primary role in protein-protein interactions and the modulation of the Wnt/β-catenin signaling pathway. LZIC is broadly expressed across various tissues and has been implicated in the cellular response to DNA damage, particularly following ionizing radiation. Functional studies indicate that LZIC levels influence radiation sensitivity and cell-cycle regulation, positioning the protein as a potential modulator of survival pathways and a candidate biomarker for cellular stress responses.