人 LY75 抗体对
01AB04087
Lymphocyte antigen 75 (LY75), also known as CD205 or DEC-205, is a protein-coding gene located on chromosome 2. It plays a crucial role in the immune system by functioning as an endocytic receptor that captures antigens for processing and presentation to T cells, thereby facilitating immune responses. The LY75 protein is primarily expressed in dendritic cells and is involved in pathways related to immune and inflammatory responses. Diseases associated with LY75 include Pneumonic Plague and Membranous Nephropathy, highlighting its significance in both infectious and autoimmune conditions. Additionally, high expression levels of LY75 have been linked to the metastasis of ovarian cancer, indicating its potential role in cancer biology. The protein has a molecular mass of approximately 198 kDa and consists of 1,722 amino acids, exhibiting significant evolutionary conservation across species.
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技术参数
- 靶点基因名
- LY75
- 基因别名
- CD205; CLEC13B
- 蛋白别名
- lymphocyte antigen 75; LY75
- UniProt
- O60449
- 物种
- Human
产品详情
- 靶点名称
- LY75
- 蛋白名称
- lymphocyte antigen 75
- 蛋白别名
- Lymphocyte antigen 75; Ly-75; C-type lectin domain family 13 member B; DEC-205; gp200-MR6; CD antigen CD205
- 靶点基因名
- LY75
- 基因别名
- CD205; CLEC13B
- UniProt
- O60449
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Lymphocyte antigen 75 (LY75), also known as CD205 or DEC-205, is a protein-coding gene located on chromosome 2. It plays a crucial role in the immune system by functioning as an endocytic receptor that captures antigens for processing and presentation to T cells, thereby facilitating immune responses. The LY75 protein is primarily expressed in dendritic cells and is involved in pathways related to immune and inflammatory responses. Diseases associated with LY75 include Pneumonic Plague and Membranous Nephropathy, highlighting its significance in both infectious and autoimmune conditions. Additionally, high expression levels of LY75 have been linked to the metastasis of ovarian cancer, indicating its potential role in cancer biology. The protein has a molecular mass of approximately 198 kDa and consists of 1,722 amino acids, exhibiting significant evolutionary conservation across species.