抗人 LAT2 抗体对
01AB03318
Linker for activation of T-cells family member 2 (LAT2) is a member of the LAT protein family, which plays a crucial role in T-cell activation and signaling. LAT2 acts as an adaptor protein that facilitates the assembly of signaling complexes following T-cell receptor engagement, thereby promoting downstream signaling pathways essential for T-cell proliferation and differentiation. It is expressed in various tissues, including immune cells, and is involved in processes such as cell adhesion and migration. Dysregulation of LAT2 has been implicated in several diseases, particularly autoimmune disorders and cancers. For instance, altered LAT2 expression can contribute to the pathogenesis of conditions like rheumatoid arthritis and systemic lupus erythematosus by affecting immune cell signaling and function. Additionally, LAT2 has been associated with tumor progression in cancers such as leukemia and lymphoma, where its signaling pathways may promote cell survival and proliferation.
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技术参数
- 靶点基因名
- LAT2
- 基因别名
- LAB; NTAL; WBS15; WBSCR15; WBSCR5
- 蛋白别名
- linker for activation of T cells family member 2; LAT2
- UniProt
- Q9GZY6
- 物种
- Human
产品详情
- 靶点名称
- LAT2
- 蛋白名称
- linker for activation of T cells family member 2
- 蛋白别名
- Linker for activation of T-cells family member 2; Linker for activation of B-cells; Membrane-associated adapter molecule; Non-T-cell activation linker; Williams-Beuren syndrome chromosomal region 15 protein; Williams-Beuren syndrome chromosomal region 5 protein
- 靶点基因名
- LAT2
- 基因别名
- LAB; NTAL; WBS15; WBSCR15; WBSCR5
- UniProt
- Q9GZY6
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Linker for activation of T-cells family member 2 (LAT2) is a member of the LAT protein family, which plays a crucial role in T-cell activation and signaling. LAT2 acts as an adaptor protein that facilitates the assembly of signaling complexes following T-cell receptor engagement, thereby promoting downstream signaling pathways essential for T-cell proliferation and differentiation. It is expressed in various tissues, including immune cells, and is involved in processes such as cell adhesion and migration. Dysregulation of LAT2 has been implicated in several diseases, particularly autoimmune disorders and cancers. For instance, altered LAT2 expression can contribute to the pathogenesis of conditions like rheumatoid arthritis and systemic lupus erythematosus by affecting immune cell signaling and function. Additionally, LAT2 has been associated with tumor progression in cancers such as leukemia and lymphoma, where its signaling pathways may promote cell survival and proliferation.