人 KRR1 抗体对
01AB03141
KRR1 small subunit processome component (KRR1) is a conserved nucleolar RNA-binding protein essential for the biogenesis of the 40S ribosomal subunit. Containing tandem K-homology (KH) domains, it functions as a core component of the small subunit processome, facilitating the processing, folding, and assembly of 18S rRNA. KRR1 cooperates with other assembly factors to drive the maturation of pre-40S particles within the nucleolus. While widely expressed and fundamental for cell viability and protein synthesis capacity, KRR1 is not currently defined as a specific driver of monogenic Mendelian diseases in humans.
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技术参数
- 靶点基因名
- KRR1
- 基因别名
- HRB2
- 蛋白别名
- KRR1 small subunit processome component; KRR1
- UniProt
- Q13601
- 物种
- Human
产品详情
- 靶点名称
- KRR1
- 蛋白名称
- KRR1 small subunit processome component
- 蛋白别名
- KRR1 small subunit processome component homolog; HIV-1 Rev-binding protein 2; KRR-R motif-containing protein 1; Rev-interacting protein 1; Rip-1
- 靶点基因名
- KRR1
- 基因别名
- HRB2
- UniProt
- Q13601
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
KRR1 small subunit processome component (KRR1) is a conserved nucleolar RNA-binding protein essential for the biogenesis of the 40S ribosomal subunit. Containing tandem K-homology (KH) domains, it functions as a core component of the small subunit processome, facilitating the processing, folding, and assembly of 18S rRNA. KRR1 cooperates with other assembly factors to drive the maturation of pre-40S particles within the nucleolus. While widely expressed and fundamental for cell viability and protein synthesis capacity, KRR1 is not currently defined as a specific driver of monogenic Mendelian diseases in humans.