人 KLHDC7B 抗体对
01AB02489
Kelch domain containing 7B (KLHDC7B) is a cytoplasmic protein characterized by a C-terminal Kelch beta-propeller domain, which typically facilitates protein-protein interactions. As a member of the Kelch family, it is involved in various cellular processes, including cytoskeletal organization and stress responses. In the context of oncology, KLHDC7B is frequently overexpressed in breast tumors and other malignancies, where it promotes cell proliferation and modulates interferon signaling pathways. Despite its promoter often being hypermethylated, its elevated expression levels serve as a significant prognostic biomarker. KLHDC7B appears to play an oncogenic role by integrating signaling inputs that drive tumor progression, although its precise physiological functions in normal tissue remain a subject of ongoing investigation.
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技术参数
- 靶点基因名
- KLHDC7B
- 蛋白别名
- kelch domain containing 7B; KLHDC7B
- UniProt
- Q96G42
- 物种
- Human
产品详情
- 靶点名称
- KLHDC7B
- 蛋白名称
- kelch domain containing 7B
- 蛋白别名
- Kelch domain-containing protein 7B
- 靶点基因名
- KLHDC7B
- UniProt
- Q96G42
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Kelch domain containing 7B (KLHDC7B) is a cytoplasmic protein characterized by a C-terminal Kelch beta-propeller domain, which typically facilitates protein-protein interactions. As a member of the Kelch family, it is involved in various cellular processes, including cytoskeletal organization and stress responses. In the context of oncology, KLHDC7B is frequently overexpressed in breast tumors and other malignancies, where it promotes cell proliferation and modulates interferon signaling pathways. Despite its promoter often being hypermethylated, its elevated expression levels serve as a significant prognostic biomarker. KLHDC7B appears to play an oncogenic role by integrating signaling inputs that drive tumor progression, although its precise physiological functions in normal tissue remain a subject of ongoing investigation.