人 ITGB1BP2 抗体对
01AB03256
Integrin beta-1-binding protein 2 (ITGB1BP2) is a protein that interacts with integrin beta-1, playing a crucial role in cell adhesion and signaling pathways. It is involved in the regulation of integrin-mediated cellular processes, including cell migration, proliferation, and survival. By binding to integrin beta-1, ITGB1BP2 helps modulate the interaction between cells and the extracellular matrix, which is essential for maintaining tissue architecture and function. Dysregulation of ITGB1BP2 has been implicated in various diseases, particularly cancer, where altered expression can affect tumor progression and metastasis. For instance, reduced levels of ITGB1BP2 have been associated with increased invasive potential in certain cancers, suggesting its role as a tumor suppressor. Additionally, its involvement in signaling pathways linked to inflammation and immune responses may contribute to autoimmune disorders.
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技术参数
- 靶点基因名
- ITGB1BP2
- 蛋白别名
- integrin subunit beta 1 binding protein 2; ITGB1BP2
- UniProt
- Q9UKP3
- 物种
- Human
产品详情
- 靶点名称
- ITGB1BP2
- 蛋白名称
- integrin subunit beta 1 binding protein 2
- 蛋白别名
- Integrin beta-1-binding protein 2; Melusin
- 靶点基因名
- ITGB1BP2
- UniProt
- Q9UKP3
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Integrin beta-1-binding protein 2 (ITGB1BP2) is a protein that interacts with integrin beta-1, playing a crucial role in cell adhesion and signaling pathways. It is involved in the regulation of integrin-mediated cellular processes, including cell migration, proliferation, and survival. By binding to integrin beta-1, ITGB1BP2 helps modulate the interaction between cells and the extracellular matrix, which is essential for maintaining tissue architecture and function. Dysregulation of ITGB1BP2 has been implicated in various diseases, particularly cancer, where altered expression can affect tumor progression and metastasis. For instance, reduced levels of ITGB1BP2 have been associated with increased invasive potential in certain cancers, suggesting its role as a tumor suppressor. Additionally, its involvement in signaling pathways linked to inflammation and immune responses may contribute to autoimmune disorders.