抗人 INTS6L 抗体对
01AB03309
Integrator complex subunit 6 like (INTS6L), also known as DDX26B, is a paralog of the Integrator subunit INTS6. It is associated with the Integrator complex, a multiprotein machinery that couples RNA polymerase II transcription with the processing of noncoding RNAs. Sharing homology with DEAD-box RNA helicases, INTS6L likely supports the scaffolding or regulatory functions of the complex, similar to INTS6, which aids in recruiting phosphatase modules. While its paralog INTS6 has established links to cancer as a tumor suppressor, specific disease associations for INTS6L remain less defined, though its structural conservation implies a contributory role in transcriptional regulation and RNA processing.
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技术参数
- 靶点基因名
- INTS6L
- 基因别名
- DDX26B
- 蛋白别名
- integrator complex subunit 6 like; INTS6L
- UniProt
- Q5JSJ4
- 物种
- Human
产品详情
- 靶点名称
- INTS6L
- 蛋白名称
- integrator complex subunit 6 like
- 蛋白别名
- Integrator complex subunit 6-like; Protein DDX26B
- 靶点基因名
- INTS6L
- 基因别名
- DDX26B
- UniProt
- Q5JSJ4
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Integrator complex subunit 6 like (INTS6L), also known as DDX26B, is a paralog of the Integrator subunit INTS6. It is associated with the Integrator complex, a multiprotein machinery that couples RNA polymerase II transcription with the processing of noncoding RNAs. Sharing homology with DEAD-box RNA helicases, INTS6L likely supports the scaffolding or regulatory functions of the complex, similar to INTS6, which aids in recruiting phosphatase modules. While its paralog INTS6 has established links to cancer as a tumor suppressor, specific disease associations for INTS6L remain less defined, though its structural conservation implies a contributory role in transcriptional regulation and RNA processing.