人 IMPA2 抗体对
01AB04187
Inositol monophosphatase 2 (IMPA2) is an enzyme encoded by the IMPA2 gene located on chromosome 18p11.2, primarily involved in the phosphatidylinositol signaling pathway, which is crucial for various cellular processes including metabolism, growth, and differentiation. The protein exhibits myo-inositol monophosphatase activity, converting myo-inositol monophosphate to myo-inositol, and is dependent on magnesium for its enzymatic function. Notably, IMPA2 has been implicated in several diseases, particularly neuropsychiatric disorders such as bipolar disorder and intellectual developmental disorder. Recent studies also highlight its role as an oncogene in cervical cancer, where it promotes tumor proliferation and metastasis through the mitogen-activated protein kinase (MAPK) signaling pathway.
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技术参数
- 靶点基因名
- IMPA2
- 基因别名
- IMP.18P
- 蛋白别名
- inositol monophosphatase 2; IMPA2
- UniProt
- O14732
- 物种
- Human
产品详情
- 靶点名称
- IMPA2
- 蛋白名称
- inositol monophosphatase 2
- 蛋白别名
- Inositol monophosphatase 2; IMP 2; IMPase 2; Inositol-1(or 4)-monophosphatase 2; Myo-inositol monophosphatase A2
- 靶点基因名
- IMPA2
- 基因别名
- IMP.18P
- UniProt
- O14732
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Inositol monophosphatase 2 (IMPA2) is an enzyme encoded by the IMPA2 gene located on chromosome 18p11.2, primarily involved in the phosphatidylinositol signaling pathway, which is crucial for various cellular processes including metabolism, growth, and differentiation. The protein exhibits myo-inositol monophosphatase activity, converting myo-inositol monophosphate to myo-inositol, and is dependent on magnesium for its enzymatic function. Notably, IMPA2 has been implicated in several diseases, particularly neuropsychiatric disorders such as bipolar disorder and intellectual developmental disorder. Recent studies also highlight its role as an oncogene in cervical cancer, where it promotes tumor proliferation and metastasis through the mitogen-activated protein kinase (MAPK) signaling pathway.