人 IL-6 抗体对
01AB03587
Interleukin-6 (IL-6) is a pleiotropic cytokine that plays a crucial role in inflammation, immunity, and disease development. IL-6 is promptly and transiently produced in response to infections and tissue injuries, contributing to host defense through the stimulation of various immune responses. However, dysregulated and persistent IL-6 production can lead to the development of various diseases, including autoimmune and chronic inflammatory disorders such as rheumatoid arthritis, systemic lupus erythematosus, and Castleman's disease. Elevated levels of IL-6 have been associated with disease activity and severity in these conditions. The pathological role of IL-6 has been demonstrated in numerous animal models, and IL-6 blockade has shown therapeutic benefits in preventing or suppressing disease development. Targeting the IL-6 signaling pathway has emerged as a rational therapeutic approach for various autoimmune and inflammatory disorders.
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技术参数
- 靶点基因名
- IL6
- 基因别名
- IFNB2
- 蛋白别名
- interleukin 6; IL6
- UniProt
- P05231
- 物种
- Human
产品详情
- 靶点名称
- IL6
- 蛋白名称
- interleukin 6
- 蛋白别名
- Interleukin-6; IL-6; B-cell stimulatory factor 2; BSF-2; CTL differentiation factor; CDF; Hybridoma growth factor; Interferon beta-2; IFN-beta-2
- 靶点基因名
- IL6
- 基因别名
- IFNB2
- UniProt
- P05231
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Interleukin-6 (IL-6) is a pleiotropic cytokine that plays a crucial role in inflammation, immunity, and disease development. IL-6 is promptly and transiently produced in response to infections and tissue injuries, contributing to host defense through the stimulation of various immune responses. However, dysregulated and persistent IL-6 production can lead to the development of various diseases, including autoimmune and chronic inflammatory disorders such as rheumatoid arthritis, systemic lupus erythematosus, and Castleman's disease. Elevated levels of IL-6 have been associated with disease activity and severity in these conditions. The pathological role of IL-6 has been demonstrated in numerous animal models, and IL-6 blockade has shown therapeutic benefits in preventing or suppressing disease development. Targeting the IL-6 signaling pathway has emerged as a rational therapeutic approach for various autoimmune and inflammatory disorders.