人 IL22 抗体对
01AB03766
IL-22 is a multifaceted cytokine that plays a crucial role in tissue homeostasis, inflammation, and host defense. It primarily targets non-hematopoietic cells, such as epithelial cells and fibroblasts, promoting their proliferation and survival. IL-22 functions as a double-edged sword in various diseases, exhibiting both protective and pathogenic effects depending on the context. In inflammatory conditions like psoriasis and inflammatory bowel disease, IL-22 can exacerbate inflammation and tissue damage. However, it also demonstrates protective functions in wound healing, tissue repair, and defense against certain infections. The balance between these opposing roles is influenced by factors such as the presence of other cytokines and the specific tissue environment. Due to its diverse effects, IL-22 has emerged as a potential therapeutic target for various conditions, including autoimmune diseases, infections, and tissue regeneration.
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技术参数
- 靶点基因名
- IL22
- 基因别名
- ILTIF; ZCYTO18
- 蛋白别名
- interleukin 22; IL22
- UniProt
- Q9GZX6
- 物种
- Human
产品详情
- 靶点名称
- IL22
- 蛋白名称
- interleukin 22
- 蛋白别名
- Interleukin-22; IL-22; Cytokine Zcyto18; IL-10-related T-cell-derived-inducible factor; IL-TIF
- 靶点基因名
- IL22
- 基因别名
- ILTIF; ZCYTO18
- UniProt
- Q9GZX6
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
IL-22 is a multifaceted cytokine that plays a crucial role in tissue homeostasis, inflammation, and host defense. It primarily targets non-hematopoietic cells, such as epithelial cells and fibroblasts, promoting their proliferation and survival. IL-22 functions as a double-edged sword in various diseases, exhibiting both protective and pathogenic effects depending on the context. In inflammatory conditions like psoriasis and inflammatory bowel disease, IL-22 can exacerbate inflammation and tissue damage. However, it also demonstrates protective functions in wound healing, tissue repair, and defense against certain infections. The balance between these opposing roles is influenced by factors such as the presence of other cytokines and the specific tissue environment. Due to its diverse effects, IL-22 has emerged as a potential therapeutic target for various conditions, including autoimmune diseases, infections, and tissue regeneration.