
人 IL-1β 抗体对
01AB02199
Interleukin-1 beta is a cytokine protein that is encoded by the IL1B gene in humans. IL-1β precursor is cleaved by cytosolic caspase 1 (interleukin 1 beta convertase) to form mature IL-1β. IL-1β is produced by activated macrophages, monocytes, and a subset of dendritic cells known as slanDC. It induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation, and cytokine production. IL-1β is involved in various physiological and pathological processes, including inflammation, immune response, and cancer. It has been associated with diseases such as gastric cancer and toxic shock syndrome.
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技术参数
- 靶点基因名
- IL1B
- 基因别名
- IL1F2
- 蛋白别名
- interleukin 1 beta; IL-1 beta
- UniProt
- P01584
- 物种
- Human
产品详情
- 靶点名称
- IL-1 beta
- 蛋白名称
- interleukin 1 beta
- 蛋白别名
- Interleukin-1 beta; IL-1 beta; Catabolin
- 靶点基因名
- IL1B
- 基因别名
- IL1F2
- UniProt
- P01584
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Interleukin-1 beta is a cytokine protein that is encoded by the IL1B gene in humans. IL-1β precursor is cleaved by cytosolic caspase 1 (interleukin 1 beta convertase) to form mature IL-1β. IL-1β is produced by activated macrophages, monocytes, and a subset of dendritic cells known as slanDC. It induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation, and cytokine production. IL-1β is involved in various physiological and pathological processes, including inflammation, immune response, and cancer. It has been associated with diseases such as gastric cancer and toxic shock syndrome.