抗人 HSPA4L 抗体对
01AB02982
Heat shock protein family A (Hsp70) member 4 like (HSPA4L) is a stress-inducible chaperone of the Hsp70 superfamily. It functions to prevent the aggregation of unfolded proteins and protect cells from proteotoxic stress, sharing structural and functional homology with HSPA4. Expressed in various tissues with enrichment in the testis, HSPA4L is critical for spermatogenesis and osmotic stress tolerance. In murine models, its deficiency leads to defects in lung maturation and fertility. In humans, HSPA4L is upregulated in certain leukemias, where it may support cell survival under stress conditions, making it a subject of interest in cancer biology.
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技术参数
- 靶点基因名
- HSPA4L
- 基因别名
- APG1; HSPH3; OSP94
- 蛋白别名
- heat shock protein family A (Hsp70) member 4 like; HSPA4L
- UniProt
- O95757
- 物种
- Human
产品详情
- 靶点名称
- HSPA4L
- 蛋白名称
- heat shock protein family A (Hsp70) member 4 like
- 蛋白别名
- Heat shock 70 kDa protein 4L; Heat shock 70-related protein APG-1; Heat shock protein family H member 3; Heat-shock protein family A member 4-like protein; HSPA4-like protein; Osmotic stress protein 94
- 靶点基因名
- HSPA4L
- 基因别名
- APG1; HSPH3; OSP94
- UniProt
- O95757
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Heat shock protein family A (Hsp70) member 4 like (HSPA4L) is a stress-inducible chaperone of the Hsp70 superfamily. It functions to prevent the aggregation of unfolded proteins and protect cells from proteotoxic stress, sharing structural and functional homology with HSPA4. Expressed in various tissues with enrichment in the testis, HSPA4L is critical for spermatogenesis and osmotic stress tolerance. In murine models, its deficiency leads to defects in lung maturation and fertility. In humans, HSPA4L is upregulated in certain leukemias, where it may support cell survival under stress conditions, making it a subject of interest in cancer biology.