人 HS3ST3B1 抗体对
01AB00266
Heparan sulfate-glucosamine 3-sulfotransferase 3B1 (HS3ST3B1) is a type II integral membrane protein belonging to the 3-O-sulfotransferases family. It catalyzes the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate, using 3'-phospho-5'-adenylyl sulfate (PAPS) as a donor. This enzyme is involved in the modification of heparan sulfate, which plays a crucial role in various biological processes, including cell signaling and viral entry. Specifically, HS3ST3B1 generates an enzyme-modified heparan sulfate that acts as a binding receptor for Herpes simplex virus-1 (HSV-1), facilitating its entry into cells. The protein is encoded by the HS3ST3B1 gene located on chromosome 17 and has been associated with diseases such as Herpes simplex and overhydrated hereditary stomatocytosis.
| 规格 | 起售价 |
|---|---|
| 登录后可查看 | |
技术参数
- 靶点基因名
- HS3ST3B1
- 基因别名
- 3OST3B1; HS3ST3B
- 蛋白别名
- heparan sulfate-glucosamine 3-sulfotransferase 3B1; HS3ST3B1
- UniProt
- Q9Y662
- 物种
- Human
产品详情
- 靶点名称
- HS3ST3B1
- 蛋白名称
- heparan sulfate-glucosamine 3-sulfotransferase 3B1
- 蛋白别名
- Heparan sulfate glucosamine 3-O-sulfotransferase 3B1; Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1; 3-OST-3B; Heparan sulfate 3-O-sulfotransferase 3B1; h3-OST-3B
- 靶点基因名
- HS3ST3B1
- 基因别名
- 3OST3B1; HS3ST3B
- UniProt
- Q9Y662
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Heparan sulfate-glucosamine 3-sulfotransferase 3B1 (HS3ST3B1) is a type II integral membrane protein belonging to the 3-O-sulfotransferases family. It catalyzes the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate, using 3'-phospho-5'-adenylyl sulfate (PAPS) as a donor. This enzyme is involved in the modification of heparan sulfate, which plays a crucial role in various biological processes, including cell signaling and viral entry. Specifically, HS3ST3B1 generates an enzyme-modified heparan sulfate that acts as a binding receptor for Herpes simplex virus-1 (HSV-1), facilitating its entry into cells. The protein is encoded by the HS3ST3B1 gene located on chromosome 17 and has been associated with diseases such as Herpes simplex and overhydrated hereditary stomatocytosis.