人 GGPS1 抗体对
01AB00505
Geranylgeranyl diphosphate synthase 1 (GGPS1) is an enzyme encoded by the GGPS1 gene, which belongs to the prenyltransferase family. It catalyzes the synthesis of geranylgeranyl diphosphate (GGPP) from farnesyl diphosphate and isopentenyl diphosphate. GGPP is crucial for the C20-prenylation of proteins and the regulation of a nuclear hormone receptor. The protein has a molecular weight of approximately 34,871 Da and a length of 300 amino acids in humans. Mutations in both copies of the GGPS1 gene have been associated with a syndrome characterized by muscular dystrophy, hearing loss, and ovarian insufficiency.
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技术参数
- 靶点基因名
- GGPS1
- 蛋白别名
- geranylgeranyl diphosphate synthase 1; GGPS1
- UniProt
- O95749
- 物种
- Human
产品详情
- 靶点名称
- GGPS1
- 蛋白名称
- geranylgeranyl diphosphate synthase 1
- 蛋白别名
- Geranylgeranyl pyrophosphate synthase; GGPP synthase; GGPPSase; (2E; 6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyltranstransferase; Geranylgeranyl diphosphate synthase; Geranyltranstransferase
- 靶点基因名
- GGPS1
- UniProt
- O95749
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Geranylgeranyl diphosphate synthase 1 (GGPS1) is an enzyme encoded by the GGPS1 gene, which belongs to the prenyltransferase family. It catalyzes the synthesis of geranylgeranyl diphosphate (GGPP) from farnesyl diphosphate and isopentenyl diphosphate. GGPP is crucial for the C20-prenylation of proteins and the regulation of a nuclear hormone receptor. The protein has a molecular weight of approximately 34,871 Da and a length of 300 amino acids in humans. Mutations in both copies of the GGPS1 gene have been associated with a syndrome characterized by muscular dystrophy, hearing loss, and ovarian insufficiency.