人 GAL 抗体对
01AB03146
Galanin peptides (GAL) are a family of neuropeptides, widely expressed in the central and peripheral nervous systems, as well as in non-neuronal tissues. The galanin family includes several members, such as galanin itself, galanin-like peptide (GALP), and alarin, which all interact with three G protein-coupled receptors (GALR1, GALR2, and GALR3). Galanin plays a crucial role in various physiological functions, including modulation of neurotransmitter release, regulation of pain perception, appetite control, and cognitive processes. Dysregulation of galanin signaling has been implicated in several diseases. For instance, elevated levels of galanin have been associated with neurodegenerative conditions like Alzheimer's disease and epilepsy, where it may contribute to neuroprotection or exacerbate seizures. Additionally, alterations in galanin expression are linked to mood disorders such as depression and anxiety, as well as metabolic disorders like obesity.
| 规格 | 起售价 |
|---|---|
| 登录后可查看 | |
技术参数
- 靶点基因名
- GAL
- 基因别名
- GAL1; GALN; GLNN
- 蛋白别名
- galanin and GMAP prepropeptide; GAL
- UniProt
- P22466
- 物种
- Human
产品详情
- 靶点名称
- GAL
- 蛋白名称
- galanin and GMAP prepropeptide
- 蛋白别名
- Galanin peptides [Cleaved into: Galanin; Galanin message-associated peptide; GMAP]
- 靶点基因名
- GAL
- 基因别名
- GAL1; GALN; GLNN
- UniProt
- P22466
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Galanin peptides (GAL) are a family of neuropeptides, widely expressed in the central and peripheral nervous systems, as well as in non-neuronal tissues. The galanin family includes several members, such as galanin itself, galanin-like peptide (GALP), and alarin, which all interact with three G protein-coupled receptors (GALR1, GALR2, and GALR3). Galanin plays a crucial role in various physiological functions, including modulation of neurotransmitter release, regulation of pain perception, appetite control, and cognitive processes. Dysregulation of galanin signaling has been implicated in several diseases. For instance, elevated levels of galanin have been associated with neurodegenerative conditions like Alzheimer's disease and epilepsy, where it may contribute to neuroprotection or exacerbate seizures. Additionally, alterations in galanin expression are linked to mood disorders such as depression and anxiety, as well as metabolic disorders like obesity.