人 FOXP4 抗体对
01AB00496
Forkhead box P4 (FOXP4) is a transcription factor gene that belongs to the forkhead box (FOX) family, specifically subfamily P. It is expressed in nearly all tissues, with the highest expression in the lungs and gut. FOXP4 plays a crucial role in the regulation of tissue- and cell type-specific gene transcription during development and adulthood. Variants in the FOXP4 gene have been associated with several diseases, including cancers, particularly lung cancer, and developmental disorders with speech/language delays. Recent studies have also identified FOXP4 as a risk factor for Long COVID, with genetic variants in the FOXP4 locus showing a significant association with the development of Long COVID, suggesting a broader role for lung function in its pathophysiology.
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技术参数
- 靶点基因名
- FOXP4
- 基因别名
- FKHLA
- 蛋白别名
- forkhead box P4; FOXP4
- UniProt
- Q8IVH2
- 物种
- Human
产品详情
- 靶点名称
- FOXP4
- 蛋白名称
- forkhead box P4
- 蛋白别名
- Forkhead box protein P4; Fork head-related protein-like A
- 靶点基因名
- FOXP4
- 基因别名
- FKHLA
- UniProt
- Q8IVH2
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Forkhead box P4 (FOXP4) is a transcription factor gene that belongs to the forkhead box (FOX) family, specifically subfamily P. It is expressed in nearly all tissues, with the highest expression in the lungs and gut. FOXP4 plays a crucial role in the regulation of tissue- and cell type-specific gene transcription during development and adulthood. Variants in the FOXP4 gene have been associated with several diseases, including cancers, particularly lung cancer, and developmental disorders with speech/language delays. Recent studies have also identified FOXP4 as a risk factor for Long COVID, with genetic variants in the FOXP4 locus showing a significant association with the development of Long COVID, suggesting a broader role for lung function in its pathophysiology.