人 FGF20 抗体对
01AB01486
Fibroblast growth factor 20 (FGF20) is a member of the FGF family, which are cell signaling proteins involved in diverse biological processes such as cellular proliferation, survival, migration, and differentiation through pathways like RAS/MAP kinase, PI3 kinase/AKT, and PLCγ. FGFs, including FGF20, interact with specific fibroblast growth factor receptors (FGFRs) on the cell surface, forming a ternary complex with heparan sulfate chains to initiate downstream signaling. These proteins are critical for tissue regeneration and development, with their biological stability and half-life being important for therapeutic applications. FGF20, like other FGFs, plays a significant role in tissue repair and homeostasis, influencing processes such as bone formation and neural development. In terms of disease, dysregulation of FGF signaling, including FGF20, has been implicated in various pathological conditions, such as impaired tissue regeneration and potentially in cancer progression, due to its effects on cell proliferation and migration.
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技术参数
- 靶点基因名
- FGF20
- 蛋白别名
- fibroblast growth factor 20; FGF20
- UniProt
- Q9NP95
- 物种
- Human
产品详情
- 靶点名称
- FGF20
- 蛋白名称
- fibroblast growth factor 20
- 蛋白别名
- Fibroblast growth factor 20; FGF-20
- 靶点基因名
- FGF20
- UniProt
- Q9NP95
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Fibroblast growth factor 20 (FGF20) is a member of the FGF family, which are cell signaling proteins involved in diverse biological processes such as cellular proliferation, survival, migration, and differentiation through pathways like RAS/MAP kinase, PI3 kinase/AKT, and PLCγ. FGFs, including FGF20, interact with specific fibroblast growth factor receptors (FGFRs) on the cell surface, forming a ternary complex with heparan sulfate chains to initiate downstream signaling. These proteins are critical for tissue regeneration and development, with their biological stability and half-life being important for therapeutic applications. FGF20, like other FGFs, plays a significant role in tissue repair and homeostasis, influencing processes such as bone formation and neural development. In terms of disease, dysregulation of FGF signaling, including FGF20, has been implicated in various pathological conditions, such as impaired tissue regeneration and potentially in cancer progression, due to its effects on cell proliferation and migration.