人 FES 抗体对
01AB03081
Tyrosine-protein kinase Fes/Fps (FES) is a non-receptor tyrosine kinase that plays a significant role in various cellular processes, including cell proliferation, differentiation, and survival. FES is primarily expressed in hematopoietic cells and is involved in signaling pathways that regulate immune responses and inflammation. Its activation is associated with the regulation of cytoskeletal dynamics and cellular adhesion, which are crucial for normal immune function. Dysregulation of FES has been implicated in several diseases, such as leukemia and lymphoma. Elevated FES expression has been observed in acute myeloid leukemia (AML), where it may contribute to oncogenic signaling and promote tumor cell survival. Additionally, FES has been linked to autoimmune diseases, including rheumatoid arthritis, where its activity can exacerbate inflammation and joint damage.
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技术参数
- 靶点基因名
- FES
- 基因别名
- FPS
- 蛋白别名
- FES proto-oncogene, tyrosine kinase; FES
- UniProt
- P07332
- 物种
- Human
产品详情
- 靶点名称
- FES
- 蛋白名称
- FES proto-oncogene, tyrosine kinase
- 蛋白别名
- Tyrosine-protein kinase Fes/Fps; Feline sarcoma/Fujinami avian sarcoma oncogene homolog; Proto-oncogene c-Fes; Proto-oncogene c-Fps; p93c-fes
- 靶点基因名
- FES
- 基因别名
- FPS
- UniProt
- P07332
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Tyrosine-protein kinase Fes/Fps (FES) is a non-receptor tyrosine kinase that plays a significant role in various cellular processes, including cell proliferation, differentiation, and survival. FES is primarily expressed in hematopoietic cells and is involved in signaling pathways that regulate immune responses and inflammation. Its activation is associated with the regulation of cytoskeletal dynamics and cellular adhesion, which are crucial for normal immune function. Dysregulation of FES has been implicated in several diseases, such as leukemia and lymphoma. Elevated FES expression has been observed in acute myeloid leukemia (AML), where it may contribute to oncogenic signaling and promote tumor cell survival. Additionally, FES has been linked to autoimmune diseases, including rheumatoid arthritis, where its activity can exacerbate inflammation and joint damage.