抗人 EXOC3L4 抗体对
01AB01134
Exocyst complex component 3 like 4 (EXOC3L4) is a protein-coding gene that belongs to the SEC6 family and is predicted to be part of the exocyst complex. It plays a crucial role in targeting SLC2A4 vesicles to the plasma membrane in response to insulin in adipocytes, potentially directing vesicles to precise fusion sites. EXOC3L4 is involved in exocyst localization and exocytosis, and is predicted to enable SNARE binding activity. The protein consists of 722 amino acids and interacts with other exocyst complex components such as EXOC4, EXOC2, and EXOC7. Recent studies have associated rare variants in the splicing regulatory elements of EXOC3L4 with brain glucose metabolism in Alzheimer's disease, suggesting a potential link between EXOC3L4 splicing, vesicle transport, and AD-related phenotypes.
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技术参数
- 靶点基因名
- EXOC3L4
- 基因别名
- C14orf73
- 蛋白别名
- exocyst complex component 3 like 4; EXOC3L4
- UniProt
- Q17RC7
- 物种
- Human
产品详情
- 靶点名称
- EXOC3L4
- 蛋白名称
- exocyst complex component 3 like 4
- 蛋白别名
- Exocyst complex component 3-like protein 4
- 靶点基因名
- EXOC3L4
- 基因别名
- C14orf73
- UniProt
- Q17RC7
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Exocyst complex component 3 like 4 (EXOC3L4) is a protein-coding gene that belongs to the SEC6 family and is predicted to be part of the exocyst complex. It plays a crucial role in targeting SLC2A4 vesicles to the plasma membrane in response to insulin in adipocytes, potentially directing vesicles to precise fusion sites. EXOC3L4 is involved in exocyst localization and exocytosis, and is predicted to enable SNARE binding activity. The protein consists of 722 amino acids and interacts with other exocyst complex components such as EXOC4, EXOC2, and EXOC7. Recent studies have associated rare variants in the splicing regulatory elements of EXOC3L4 with brain glucose metabolism in Alzheimer's disease, suggesting a potential link between EXOC3L4 splicing, vesicle transport, and AD-related phenotypes.