人 eIF5A 抗体对
01AB03067
Eukaryotic translation initiation factor 5A-1 (EIF5A) is an evolutionarily conserved protein that plays a crucial role in protein synthesis, particularly in the translation of mRNAs containing consecutive proline residues. EIF5A is unique due to its post-translational modification known as hypusination, which is essential for its function. It binds to ribosomes and facilitates the elongation phase of translation, enhancing the synthesis of specific proteins that are critical for cell proliferation, differentiation, and survival. Dysregulation of EIF5A has been implicated in various diseases, including cancer, where altered expression can contribute to tumor growth and metastasis. Additionally, EIF5A has been linked to viral infections and metabolic disorders like diabetes.
| 规格 | 起售价 |
|---|---|
| 登录后可查看 | |
技术参数
- 靶点基因名
- EIF5A
- 蛋白别名
- eukaryotic translation initiation factor 5A; eIF5A
- UniProt
- P63241
- 物种
- Human
产品详情
- 靶点名称
- eIF5A
- 蛋白名称
- eukaryotic translation initiation factor 5A
- 蛋白别名
- Eukaryotic translation initiation factor 5A-1; eIF-5A-1; eIF-5A1; Eukaryotic initiation factor 5A isoform 1; eIF-5A; Rev-binding factor; eIF-4D
- 靶点基因名
- EIF5A
- UniProt
- P63241
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Eukaryotic translation initiation factor 5A-1 (EIF5A) is an evolutionarily conserved protein that plays a crucial role in protein synthesis, particularly in the translation of mRNAs containing consecutive proline residues. EIF5A is unique due to its post-translational modification known as hypusination, which is essential for its function. It binds to ribosomes and facilitates the elongation phase of translation, enhancing the synthesis of specific proteins that are critical for cell proliferation, differentiation, and survival. Dysregulation of EIF5A has been implicated in various diseases, including cancer, where altered expression can contribute to tumor growth and metastasis. Additionally, EIF5A has been linked to viral infections and metabolic disorders like diabetes.