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人 Drebrin 抗体对
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人 Drebrin 抗体对

01AB03658

Drebrin 1 (DBN1) is an actin cytoskeleton-organizing protein that plays a crucial role in the formation of cell projections and is particularly significant in neuronal development and function. It is involved in actin polymerization and is required for the proper organization of the actin cytoskeleton, which is essential for cell shape and movement. DBN1 is predominantly expressed in the brain, including regions such as the hippocampal formation, amygdala, basal ganglia, and cerebral cortex. In neurons, DBN1 is thought to regulate synaptic plasticity and the targeting of NMDA receptors. While primarily associated with neural functions, recent studies have also implicated DBN1 in myofibroblast differentiation and the promotion of fibrosis-related genes in the heart and lungs.

Human
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技术参数

靶点基因名
DBN1
基因别名
D0S117E
蛋白别名
drebrin 1; Drebrin
UniProt
Q16643
物种
Human

产品详情

靶点名称
Drebrin
蛋白名称
drebrin 1
蛋白别名
Drebrin; Developmentally-regulated brain protein
靶点基因名
DBN1
基因别名
D0S117E
UniProt
Q16643
来源物种
Homo sapiens (Human)
物种反应性
Human

背景介绍

Drebrin 1 (DBN1) is an actin cytoskeleton-organizing protein that plays a crucial role in the formation of cell projections and is particularly significant in neuronal development and function. It is involved in actin polymerization and is required for the proper organization of the actin cytoskeleton, which is essential for cell shape and movement. DBN1 is predominantly expressed in the brain, including regions such as the hippocampal formation, amygdala, basal ganglia, and cerebral cortex. In neurons, DBN1 is thought to regulate synaptic plasticity and the targeting of NMDA receptors. While primarily associated with neural functions, recent studies have also implicated DBN1 in myofibroblast differentiation and the promotion of fibrosis-related genes in the heart and lungs.