人 DIAPH2 抗体对
01AB02598
Diaphanous related formin 2 (DIAPH2) is an X-linked formin protein that regulates actin filament elongation and microtubule stabilization. It contains formin homology (FH1 and FH2) domains that mediate actin binding and polymerization, alongside regulatory regions that interact with Rho GTPases such as RhoD. Through these interactions, DIAPH2 controls endosome dynamics and early endosome motility via the actin cytoskeleton. It is expressed in various tissues, including the ovary, where it is thought to participate in oogenesis and the maintenance of normal ovarian function. As a member of the diaphanous subfamily, DIAPH2 serves as a key effector in Rho-mediated remodeling of the cellular cytoskeleton.
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技术参数
- 靶点基因名
- DIAPH2
- 基因别名
- DIA
- 蛋白别名
- diaphanous related formin 2; DIAPH2
- UniProt
- O60879
- 物种
- Human
产品详情
- 靶点名称
- DIAPH2
- 蛋白名称
- diaphanous related formin 2
- 蛋白别名
- Protein diaphanous homolog 2; Diaphanous-related formin-2; DRF2
- 靶点基因名
- DIAPH2
- 基因别名
- DIA
- UniProt
- O60879
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Diaphanous related formin 2 (DIAPH2) is an X-linked formin protein that regulates actin filament elongation and microtubule stabilization. It contains formin homology (FH1 and FH2) domains that mediate actin binding and polymerization, alongside regulatory regions that interact with Rho GTPases such as RhoD. Through these interactions, DIAPH2 controls endosome dynamics and early endosome motility via the actin cytoskeleton. It is expressed in various tissues, including the ovary, where it is thought to participate in oogenesis and the maintenance of normal ovarian function. As a member of the diaphanous subfamily, DIAPH2 serves as a key effector in Rho-mediated remodeling of the cellular cytoskeleton.