人 DHRS9 抗体对
01AB01681
Dehydrogenase/reductase 9 (DHRS9) is a short-chain dehydrogenase/reductase that functions as both a 3-alpha-hydroxysteroid dehydrogenase and a retinol dehydrogenase. It plays a key role in the biosynthesis of retinoic acid from retinaldehyde and catalyzes the oxidation of steroids such as allopregnanolone and androstanediol. DHRS9 is primarily expressed in epithelial and immune tissues, where it utilizes NADH or NADPH as cofactors to modulate retinoic acid and steroid hormone signaling pathways. Beyond its metabolic activity, it has been described as a moonlighting protein that may act as a nuclear transcriptional repressor. DHRS9 is fundamentally involved in retinoic acid-mediated transcriptional programs and visual retinoid signaling, contributing to cellular differentiation and hormonal regulation.
| 规格 | 起售价 |
|---|---|
| 登录后可查看 | |
技术参数
- 靶点基因名
- DHRS9
- 基因别名
- RDH15; SDR9C4
- 蛋白别名
- dehydrogenase/reductase 9; DHRS9
- UniProt
- Q9BPW9
- 物种
- Human
产品详情
- 靶点名称
- DHRS9
- 蛋白名称
- dehydrogenase/reductase 9
- 蛋白别名
- Dehydrogenase/reductase SDR family member 9; 3-alpha hydroxysteroid dehydrogenase; 3-alpha-HSD; NADP-dependent retinol dehydrogenase/reductase; RDH-E2; RDHL; Retinol dehydrogenase 15; Short chain dehydrogenase/reductase family 9C member 4; Short-chain dehydrogenase/reductase retSDR8; Tracheobronchial epithelial cell-specific retinol dehydrogenase; RDH-TBE
- 靶点基因名
- DHRS9
- 基因别名
- RDH15; SDR9C4
- UniProt
- Q9BPW9
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Dehydrogenase/reductase 9 (DHRS9) is a short-chain dehydrogenase/reductase that functions as both a 3-alpha-hydroxysteroid dehydrogenase and a retinol dehydrogenase. It plays a key role in the biosynthesis of retinoic acid from retinaldehyde and catalyzes the oxidation of steroids such as allopregnanolone and androstanediol. DHRS9 is primarily expressed in epithelial and immune tissues, where it utilizes NADH or NADPH as cofactors to modulate retinoic acid and steroid hormone signaling pathways. Beyond its metabolic activity, it has been described as a moonlighting protein that may act as a nuclear transcriptional repressor. DHRS9 is fundamentally involved in retinoic acid-mediated transcriptional programs and visual retinoid signaling, contributing to cellular differentiation and hormonal regulation.