人 DGKZ 抗体对
01AB03037
Diacylglycerol kinase zeta (DGKZ) is an enzyme that belongs to the diacylglycerol kinase family, responsible for phosphorylating diacylglycerol (DAG) to produce phosphatidic acid (PA), a key lipid signaling molecule. DGKZ contains a conserved catalytic domain and is characterized by its ability to modulate intracellular signaling pathways, particularly those involving protein kinase C (PKC). By regulating DAG levels, DGKZ plays a crucial role in various cellular processes, including cell growth, differentiation, and apoptosis. Dysregulation of DGKZ has been implicated in several diseases, notably cancer; altered expression of DGKZ can affect tumor cell proliferation and survival. Additionally, studies have suggested that DGKZ may be involved in neurodegenerative diseases and inflammatory conditions due to its role in modulating signaling pathways linked to cell survival and inflammation.
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技术参数
- 靶点基因名
- DGKZ
- 基因别名
- DAGK6
- 蛋白别名
- diacylglycerol kinase zeta; DGKZ
- UniProt
- Q13574-1
- 物种
- Human
产品详情
- 靶点名称
- DGKZ
- 蛋白名称
- diacylglycerol kinase zeta
- 蛋白别名
- diacylglycerol kinase zeta
- 靶点基因名
- DGKZ
- 基因别名
- DAGK6
- UniProt
- Q13574-1
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Diacylglycerol kinase zeta (DGKZ) is an enzyme that belongs to the diacylglycerol kinase family, responsible for phosphorylating diacylglycerol (DAG) to produce phosphatidic acid (PA), a key lipid signaling molecule. DGKZ contains a conserved catalytic domain and is characterized by its ability to modulate intracellular signaling pathways, particularly those involving protein kinase C (PKC). By regulating DAG levels, DGKZ plays a crucial role in various cellular processes, including cell growth, differentiation, and apoptosis. Dysregulation of DGKZ has been implicated in several diseases, notably cancer; altered expression of DGKZ can affect tumor cell proliferation and survival. Additionally, studies have suggested that DGKZ may be involved in neurodegenerative diseases and inflammatory conditions due to its role in modulating signaling pathways linked to cell survival and inflammation.