人 DECR1 抗体对
01AB00212
2,4-dienoyl-CoA reductase 1 (DECR1) is a protein encoded by the DECR1 gene in humans. It functions as an auxiliary enzyme in the beta-oxidation and metabolism of unsaturated fatty enoyl-CoA esters, specifically those with double bonds in both even- and odd-numbered positions. This enzyme plays a crucial role in lipid metabolism and is involved in the positive regulation of cold-induced thermogenesis. DECR1 has been associated with various diseases, including its role as an androgen-repressed survival factor that protects prostate tumor cells from ferroptosis by regulating PUFA oxidation. Additionally, reduced DECR1 expression has been linked to immune infiltration in cervical cancer, serving as an unfavorable biomarker.
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技术参数
- 靶点基因名
- DECR1
- 基因别名
- DECR; SDR18C1
- 蛋白别名
- 2,4-dienoyl-CoA reductase 1; DECR1
- UniProt
- Q16698
- 物种
- Human
产品详情
- 靶点名称
- DECR1
- 蛋白名称
- 2,4-dienoyl-CoA reductase 1
- 蛋白别名
- 2; 4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]; mitochondrial; 2; 4-dienoyl-CoA reductase [NADPH]; 4-enoyl-CoA reductase [NADPH]; Short chain dehydrogenase/reductase family 18C member 1
- 靶点基因名
- DECR1
- 基因别名
- DECR; SDR18C1
- UniProt
- Q16698
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
2,4-dienoyl-CoA reductase 1 (DECR1) is a protein encoded by the DECR1 gene in humans. It functions as an auxiliary enzyme in the beta-oxidation and metabolism of unsaturated fatty enoyl-CoA esters, specifically those with double bonds in both even- and odd-numbered positions. This enzyme plays a crucial role in lipid metabolism and is involved in the positive regulation of cold-induced thermogenesis. DECR1 has been associated with various diseases, including its role as an androgen-repressed survival factor that protects prostate tumor cells from ferroptosis by regulating PUFA oxidation. Additionally, reduced DECR1 expression has been linked to immune infiltration in cervical cancer, serving as an unfavorable biomarker.