人 CXCL6 抗体对
01AB02714
C-X-C motif chemokine 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family, primarily involved in the immune response. It functions as a potent chemoattractant for neutrophils, facilitating their migration to sites of infection or inflammation by interacting with the receptors CXCR1 and CXCR2. In addition to its chemotactic properties, CXCL6 exhibits significant antibacterial activity against both Gram-positive and Gram-negative bacteria, enhancing its role in innate immunity. Dysregulation of CXCL6 has been implicated in various diseases, including inflammatory conditions such as rheumatoid arthritis and chronic obstructive pulmonary disease (COPD), where it contributes to sustained inflammation and tissue damage. Furthermore, CXCL6 is associated with cancer progression, as it can promote tumor growth and metastasis by enhancing angiogenesis and facilitating the recruitment of immune cells that may support tumor environments.
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技术参数
- 靶点基因名
- CXCL6
- 基因别名
- GCP2; SCYB6
- 蛋白别名
- C-X-C motif chemokine ligand 6; CXCL6
- UniProt
- P80162
- 物种
- Human
产品详情
- 靶点名称
- CXCL6
- 蛋白名称
- C-X-C motif chemokine ligand 6
- 蛋白别名
- C-X-C motif chemokine 6; Chemokine alpha 3; CKA-3; Granulocyte chemotactic protein 2; GCP-2; Small-inducible cytokine B6) [Cleaved into: Small-inducible cytokine B6; N-processed variant 1; Small-inducible cytokine B6; N-processed variant 2; Small-inducible cytokine B6; N-processed variant 3]
- 靶点基因名
- CXCL6
- 基因别名
- GCP2; SCYB6
- UniProt
- P80162
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
C-X-C motif chemokine 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family, primarily involved in the immune response. It functions as a potent chemoattractant for neutrophils, facilitating their migration to sites of infection or inflammation by interacting with the receptors CXCR1 and CXCR2. In addition to its chemotactic properties, CXCL6 exhibits significant antibacterial activity against both Gram-positive and Gram-negative bacteria, enhancing its role in innate immunity. Dysregulation of CXCL6 has been implicated in various diseases, including inflammatory conditions such as rheumatoid arthritis and chronic obstructive pulmonary disease (COPD), where it contributes to sustained inflammation and tissue damage. Furthermore, CXCL6 is associated with cancer progression, as it can promote tumor growth and metastasis by enhancing angiogenesis and facilitating the recruitment of immune cells that may support tumor environments.