人 CTBS 抗体对
01AB02470
Chitobiase (CTBS) is a lysosomal exoglycosidase that plays a critical role in the ordered degradation of N-linked glycoproteins. As a di-N-acetylchitobiase, it specifically cleaves the N-acetyl-beta-D-glucosamine(1-4)N-acetylglucosamine chitobiose core from the reducing end following the action of glycosylasparaginase. The enzyme localizes to the lysosomal compartment where it exhibits hydrolase and chitinase activities toward chitobiose and chitin-oligosaccharides, ultimately generating N-acetylglucosamine. Through these activities, CTBS contributes to essential lysosomal carbohydrate catabolism and the turnover of cellular glycoproteins.
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技术参数
- 靶点基因名
- CTBS
- 基因别名
- CTB
- 蛋白别名
- chitobiase; CTBS
- UniProt
- Q01459
- 物种
- Human
产品详情
- 靶点名称
- CTBS
- 蛋白名称
- chitobiase
- 蛋白别名
- Di-N-acetylchitobiase
- 靶点基因名
- CTBS
- 基因别名
- CTB
- UniProt
- Q01459
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Chitobiase (CTBS) is a lysosomal exoglycosidase that plays a critical role in the ordered degradation of N-linked glycoproteins. As a di-N-acetylchitobiase, it specifically cleaves the N-acetyl-beta-D-glucosamine(1-4)N-acetylglucosamine chitobiose core from the reducing end following the action of glycosylasparaginase. The enzyme localizes to the lysosomal compartment where it exhibits hydrolase and chitinase activities toward chitobiose and chitin-oligosaccharides, ultimately generating N-acetylglucosamine. Through these activities, CTBS contributes to essential lysosomal carbohydrate catabolism and the turnover of cellular glycoproteins.