人 CINP 抗体对
01AB03979
Cyclin-dependent kinase 2-interacting protein 1 (CINP) is a nuclear protein that plays a pivotal role in the regulation of the cell cycle and DNA replication. It is characterized by its ability to interact with cyclin-dependent kinase 2 (CDK2) and is involved in the DNA damage response, particularly during S-phase of the cell cycle. CINP is essential for maintaining genomic stability, as it helps coordinate the activities of various proteins involved in DNA repair and replication fork progression. Dysregulation of CINP has been linked to several diseases, particularly cancer, where its altered expression can lead to uncontrolled cell proliferation and resistance to apoptosis. Additionally, CINP has been implicated in neurodegenerative diseases due to its role in cellular stress responses.
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技术参数
- 靶点基因名
- CINP
- 蛋白别名
- cyclin dependent kinase 2 interacting protein; CINP
- UniProt
- Q9BW66
- 物种
- Human
产品详情
- 靶点名称
- CINP
- 蛋白名称
- cyclin dependent kinase 2 interacting protein
- 蛋白别名
- Cyclin-dependent kinase 2-interacting protein; CDK2-interacting protein
- 靶点基因名
- CINP
- UniProt
- Q9BW66
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Cyclin-dependent kinase 2-interacting protein 1 (CINP) is a nuclear protein that plays a pivotal role in the regulation of the cell cycle and DNA replication. It is characterized by its ability to interact with cyclin-dependent kinase 2 (CDK2) and is involved in the DNA damage response, particularly during S-phase of the cell cycle. CINP is essential for maintaining genomic stability, as it helps coordinate the activities of various proteins involved in DNA repair and replication fork progression. Dysregulation of CINP has been linked to several diseases, particularly cancer, where its altered expression can lead to uncontrolled cell proliferation and resistance to apoptosis. Additionally, CINP has been implicated in neurodegenerative diseases due to its role in cellular stress responses.