抗人 CHST2 抗体对
01AB00670
Carbohydrate sulfotransferase 2 (CHST2) is an enzyme encoded by the CHST2 gene in humans. It catalyzes the sulfation of non-reducing N-acetylglucosamine residues, specifically transferring sulfate to the 6th position of these residues. CHST2 is involved in the biosynthesis of keratan sulfate and glycosaminoglycan metabolism, playing a role in the formation of the extracellular matrix and connective tissues. The broader family of carbohydrate sulfotransferases (CHSTs) has been implicated in various conditions, including connective tissue disorders, cancer, and inflammation, due to their roles in cartilage and bone formation and the migration of inflammatory and cancer cells.
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技术参数
- 靶点基因名
- CHST2
- 基因别名
- GN6ST
- 蛋白别名
- carbohydrate sulfotransferase 2; CHST2
- UniProt
- Q9Y4C5
- 物种
- Human
产品详情
- 靶点名称
- CHST2
- 蛋白名称
- carbohydrate sulfotransferase 2
- 蛋白别名
- Carbohydrate sulfotransferase 2; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 2; GST-2; N-acetylglucosamine 6-O-sulfotransferase 1; GlcNAc6ST-1; Gn6ST-1
- 靶点基因名
- CHST2
- 基因别名
- GN6ST
- UniProt
- Q9Y4C5
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Carbohydrate sulfotransferase 2 (CHST2) is an enzyme encoded by the CHST2 gene in humans. It catalyzes the sulfation of non-reducing N-acetylglucosamine residues, specifically transferring sulfate to the 6th position of these residues. CHST2 is involved in the biosynthesis of keratan sulfate and glycosaminoglycan metabolism, playing a role in the formation of the extracellular matrix and connective tissues. The broader family of carbohydrate sulfotransferases (CHSTs) has been implicated in various conditions, including connective tissue disorders, cancer, and inflammation, due to their roles in cartilage and bone formation and the migration of inflammatory and cancer cells.