人 CDX2 抗体对
01AB00537
CDX2 is a gene that encodes for the CDX2 protein, a homeobox transcription factor expressed in the nuclei of intestinal epithelial cells, playing an essential role in the development and function of the digestive system. CDX2 is a sensitive marker for assessing intestinal phenotypic expression in undifferentiated-type adenocarcinoma of the stomach. CDX2 regulates several essential processes in the development and function of the lower gastrointestinal tract. Reduced CDX2 expression has been linked to more aggressive tumor features such as TNM stage, metastasis, and vessel invasion in colorectal cancer. CDX2 is an adverse and independent prognostic factor for overall survival in colorectal cancer patients.
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技术参数
- 靶点基因名
- CDX2
- 基因别名
- CDX3
- 蛋白别名
- caudal type homeobox 2; CDX2
- UniProt
- Q99626
- 物种
- Human
产品详情
- 靶点名称
- CDX2
- 蛋白名称
- caudal type homeobox 2
- 蛋白别名
- Homeobox protein CDX-2; CDX-3; Caudal-type homeobox protein 2
- 靶点基因名
- CDX2
- 基因别名
- CDX3
- UniProt
- Q99626
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
CDX2 is a gene that encodes for the CDX2 protein, a homeobox transcription factor expressed in the nuclei of intestinal epithelial cells, playing an essential role in the development and function of the digestive system. CDX2 is a sensitive marker for assessing intestinal phenotypic expression in undifferentiated-type adenocarcinoma of the stomach. CDX2 regulates several essential processes in the development and function of the lower gastrointestinal tract. Reduced CDX2 expression has been linked to more aggressive tumor features such as TNM stage, metastasis, and vessel invasion in colorectal cancer. CDX2 is an adverse and independent prognostic factor for overall survival in colorectal cancer patients.