人 CD83 抗体对
01AB02805
CD83 is a member of the immunoglobulin superfamily that plays a crucial role in regulating immune responses. It is expressed on the surface of various activated immune cells, including dendritic cells, B cells, T cells, and macrophages. CD83 exists in both membrane-bound and soluble forms, with the soluble form potentially having immunosuppressive functions. Interestingly, CD83 is not a typical co-stimulatory molecule but rather acts as an immune checkpoint, controlling and resolving immune responses. It is essential for the differentiation of T and B cells and the development and maintenance of immune tolerance. CD83 has been identified as a promising therapeutic target, with preclinical studies demonstrating its immunomodulatory potential in various disease models.
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技术参数
- 靶点基因名
- CD83
- 蛋白别名
- CD83 molecule; CD83
- UniProt
- Q01151
- 物种
- Human
产品详情
- 靶点名称
- CD83
- 蛋白名称
- CD83 molecule
- 蛋白别名
- CD83 antigen; hCD83; B-cell activation protein; Cell surface protein HB15; CD antigen CD83
- 靶点基因名
- CD83
- UniProt
- Q01151
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
CD83 is a member of the immunoglobulin superfamily that plays a crucial role in regulating immune responses. It is expressed on the surface of various activated immune cells, including dendritic cells, B cells, T cells, and macrophages. CD83 exists in both membrane-bound and soluble forms, with the soluble form potentially having immunosuppressive functions. Interestingly, CD83 is not a typical co-stimulatory molecule but rather acts as an immune checkpoint, controlling and resolving immune responses. It is essential for the differentiation of T and B cells and the development and maintenance of immune tolerance. CD83 has been identified as a promising therapeutic target, with preclinical studies demonstrating its immunomodulatory potential in various disease models.