抗人 CD63 抗体对
01AB00754
CD63 is a transmembrane protein that is primarily associated with the membranes of intracellular vesicles, although it can also be expressed on the cell surface. It is a member of the tetraspanin family of proteins, which are involved in cell signaling, development, activation, growth, and motility. CD63 is often used as a marker for multivesicular bodies and extracellular vesicles, as it is enriched in these structures. It is also a recognized marker for activated basophils, and is used in the basophil activation test for diagnosing IgE-mediated allergies. Deficiency of CD63 is associated with Hermansky-Pudlak Syndrome, a rare genetic disorder characterized by albinism, bleeding, and lung disease. CD63 has also been linked to tumor progression. In summary, CD63 is a multifunctional protein involved in various cellular processes, including vesicle trafficking, cell signaling, and immune function.
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技术参数
- 靶点基因名
- CD63
- 基因别名
- MLA1; TSPAN30
- 蛋白别名
- CD63 molecule; CD63
- UniProt
- P08962-1
- 物种
- Human
产品详情
- 靶点名称
- CD63
- 蛋白名称
- CD63 molecule
- 蛋白别名
- CD63 antigen; Granulophysin; Lysosomal-associated membrane protein 3; LAMP-3; Lysosome integral membrane protein 1; Limp1; Melanoma-associated antigen ME491; OMA81H; Ocular melanoma-associated antigen; Tetraspanin-30; Tspan-30; CD antigen CD63
- 靶点基因名
- CD63
- 基因别名
- MLA1; TSPAN30
- UniProt
- P08962-1
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
CD63 is a transmembrane protein that is primarily associated with the membranes of intracellular vesicles, although it can also be expressed on the cell surface. It is a member of the tetraspanin family of proteins, which are involved in cell signaling, development, activation, growth, and motility. CD63 is often used as a marker for multivesicular bodies and extracellular vesicles, as it is enriched in these structures. It is also a recognized marker for activated basophils, and is used in the basophil activation test for diagnosing IgE-mediated allergies. Deficiency of CD63 is associated with Hermansky-Pudlak Syndrome, a rare genetic disorder characterized by albinism, bleeding, and lung disease. CD63 has also been linked to tumor progression. In summary, CD63 is a multifunctional protein involved in various cellular processes, including vesicle trafficking, cell signaling, and immune function.