抗人 CCL7 抗体对
01AB00658
C-C motif chemokine ligand 7 (CCL7), also known as monocyte chemotactic protein 3 (MCP-3), is a small cytokine belonging to the CC chemokine family. It is closely related to CCL2 (MCP-1) and plays a crucial role in immune responses by attracting monocytes, eosinophils, basophils, dendritic cells, neutrophils, NK cells, and activated T lymphocytes to sites of inflammation. CCL7 is produced by various cell types, including stromal cells, keratinocytes, airway smooth muscle cells, and tumor cells. It mediates its effects through binding to multiple receptors, including CCR1, CCR2, CCR3, CCR5, and CCR10, which are G protein-coupled seven-transmembrane receptors. CCL7 is involved in antibacterial, antiviral, and antifungal immune responses and has been implicated in the pathogenesis of cardiovascular diseases and tumor progression.
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技术参数
- 靶点基因名
- CCL7
- 基因别名
- MCP3; SCYA6; SCYA7
- 蛋白别名
- C-C motif chemokine ligand 7; CCL7
- UniProt
- P80098
- 物种
- Human
产品详情
- 靶点名称
- CCL7
- 蛋白名称
- C-C motif chemokine ligand 7
- 蛋白别名
- C-C motif chemokine 7; Monocyte chemoattractant protein 3; Monocyte chemotactic protein 3; MCP-3; NC28; Small-inducible cytokine A7
- 靶点基因名
- CCL7
- 基因别名
- MCP3; SCYA6; SCYA7
- UniProt
- P80098
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
C-C motif chemokine ligand 7 (CCL7), also known as monocyte chemotactic protein 3 (MCP-3), is a small cytokine belonging to the CC chemokine family. It is closely related to CCL2 (MCP-1) and plays a crucial role in immune responses by attracting monocytes, eosinophils, basophils, dendritic cells, neutrophils, NK cells, and activated T lymphocytes to sites of inflammation. CCL7 is produced by various cell types, including stromal cells, keratinocytes, airway smooth muscle cells, and tumor cells. It mediates its effects through binding to multiple receptors, including CCR1, CCR2, CCR3, CCR5, and CCR10, which are G protein-coupled seven-transmembrane receptors. CCL7 is involved in antibacterial, antiviral, and antifungal immune responses and has been implicated in the pathogenesis of cardiovascular diseases and tumor progression.