人 CCDC81 抗体对
01AB00750
Coiled-coil domain containing 81 (CCDC81) is a protein predicted to enable DNA binding activity and is located in the centrosome and ciliary basal body. It contains two N-terminal HU domains fused to a C-terminal coiled-coil region, with the eukaryotic versions displaying a tandem duplication of the HU domain within the same polypeptide. CCDC81 is involved in centrosome organization and potentially acts as a cargo-binding protein in conjunction with Dynein-VII. The protein is expressed in various tissues, including the brain, reproductive system, and immune cells. CCDC81 has been associated with genome-wide association studies of eosinophilic esophagitis, suggesting a potential role in allergic diseases. Additionally, alterations in CCDC81 expression have been observed in response to various chemical exposures, indicating its potential involvement in cellular stress responses.
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技术参数
- 靶点基因名
- CCDC81
- 蛋白别名
- coiled-coil domain containing 81; CCDC81
- UniProt
- Q6ZN84
- 物种
- Human
产品详情
- 靶点名称
- CCDC81
- 蛋白名称
- coiled-coil domain containing 81
- 蛋白别名
- Coiled-coil domain-containing protein 81
- 靶点基因名
- CCDC81
- UniProt
- Q6ZN84
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Coiled-coil domain containing 81 (CCDC81) is a protein predicted to enable DNA binding activity and is located in the centrosome and ciliary basal body. It contains two N-terminal HU domains fused to a C-terminal coiled-coil region, with the eukaryotic versions displaying a tandem duplication of the HU domain within the same polypeptide. CCDC81 is involved in centrosome organization and potentially acts as a cargo-binding protein in conjunction with Dynein-VII. The protein is expressed in various tissues, including the brain, reproductive system, and immune cells. CCDC81 has been associated with genome-wide association studies of eosinophilic esophagitis, suggesting a potential role in allergic diseases. Additionally, alterations in CCDC81 expression have been observed in response to various chemical exposures, indicating its potential involvement in cellular stress responses.