人 CCDC127 抗体对
01AB03043
Coiled-coil domain containing 127 (CCDC127) is a small mitochondrial protein that serves as a regulator of cellular stress responses and lipid metabolism. It has been identified as a suppressor of Hsp70 gene expression, suggesting a role in transcriptional regulation during periods of cellular stress. Recent functional studies indicate that CCDC127 is involved in maintaining lipid droplet homeostasis by enhancing contact sites between the mitochondria and the endoplasmic reticulum. This localization and activity link the protein to the coordination of cellular energy and lipid processing. As an evolutionarily conserved protein across vertebrates, CCDC127 appears to play a fundamental role in integrating mitochondrial function with broader metabolic and stress-response pathways within the cell.
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技术参数
- 靶点基因名
- CCDC127
- 蛋白别名
- coiled-coil domain containing 127; CCDC127
- UniProt
- Q96BQ5
- 物种
- Human
产品详情
- 靶点名称
- CCDC127
- 蛋白名称
- coiled-coil domain containing 127
- 蛋白别名
- Coiled-coil domain-containing protein 127
- 靶点基因名
- CCDC127
- UniProt
- Q96BQ5
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Coiled-coil domain containing 127 (CCDC127) is a small mitochondrial protein that serves as a regulator of cellular stress responses and lipid metabolism. It has been identified as a suppressor of Hsp70 gene expression, suggesting a role in transcriptional regulation during periods of cellular stress. Recent functional studies indicate that CCDC127 is involved in maintaining lipid droplet homeostasis by enhancing contact sites between the mitochondria and the endoplasmic reticulum. This localization and activity link the protein to the coordination of cellular energy and lipid processing. As an evolutionarily conserved protein across vertebrates, CCDC127 appears to play a fundamental role in integrating mitochondrial function with broader metabolic and stress-response pathways within the cell.