抗人 Caspase-3 抗体对
01AB02837
Caspase-3 is a protein encoded by the CASP3 gene that plays a key role in the execution-phase of cell apoptosis. It is a member of the cysteine-aspartic acid protease (caspase) family and is formed from a 32 kDa zymogen that is cleaved into 17 kDa and 12 kDa subunits. Although caspase-3 is primarily known for its role in apoptosis, recent studies suggest that it may also play a role in non-apoptotic processes such as embryonic and hematopoietic stem cell differentiation, neurogenesis, and synaptic activity. Caspase-3 has also been identified as a potential therapeutic target for the treatment of apoptosis-related disorders such as cancers, heart failure, and neurodegenerative disorders.
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技术参数
- 靶点基因名
- CASP3
- 基因别名
- CPP32
- 蛋白别名
- caspase 3; Caspase-3
- UniProt
- P42574
- 物种
- Human
产品详情
- 靶点名称
- Caspase-3
- 蛋白名称
- caspase 3
- 蛋白别名
- Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]
- 靶点基因名
- CASP3
- 基因别名
- CPP32
- UniProt
- P42574
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Caspase-3 is a protein encoded by the CASP3 gene that plays a key role in the execution-phase of cell apoptosis. It is a member of the cysteine-aspartic acid protease (caspase) family and is formed from a 32 kDa zymogen that is cleaved into 17 kDa and 12 kDa subunits. Although caspase-3 is primarily known for its role in apoptosis, recent studies suggest that it may also play a role in non-apoptotic processes such as embryonic and hematopoietic stem cell differentiation, neurogenesis, and synaptic activity. Caspase-3 has also been identified as a potential therapeutic target for the treatment of apoptosis-related disorders such as cancers, heart failure, and neurodegenerative disorders.